Adena was the home of Thomas Worthington, one of Ohio's first two United States senators. Worthington also served as the sixth governor of the state.
Adena is a Hebrew word that means "delightful place." Worthington built his home on five thousand acres of land near Chillicothe. Benjamin Henry Latrobe, the architect who helped design the White House and the Capitol in Washington, DC, designed Adena.
Adena is an Ohio Historical Society site and has been restored. Five other buildings on the estate have also been restored or reconstructed.